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Phylum-level analyses indicate predominant Firmicutes with relative Bacteroidetes reduction in some studies (264, 265), while others report increased Actinobacteria , Verrucomicrobia , or pro-inflammatory Proteobacteria , alongside potential reduction of beneficial Bacteroidetes and Actinobacteria ( 262, 266)

Some maintain rigorous standards comparable to commercial manufacturers, while others cut corners

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Excessive intracellular copper levels induce cell death mechanisms such as autophagy and ferroptosis